SELECT 
  * 
FROM 
  cscart_bm_layouts 
WHERE 
  1 
  AND storefront_id = 1 
  AND layout_id = 2

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "nested_loop": [
      {
        "table": {
          "table_name": "cscart_bm_layouts",
          "access_type": "const",
          "possible_keys": ["PRIMARY"],
          "key": "PRIMARY",
          "key_length": "4",
          "used_key_parts": ["layout_id"],
          "ref": ["const"],
          "rows": 1,
          "filtered": 100
        }
      }
    ]
  }
}

Result

layout_id name is_default width layout_width min_width max_width theme_name style_id storefront_id
2 Main 1 16 fluid 280 1200 responsive Shavgun 1