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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd85d40ef0f4bb0a3b8777c2da341a8a51350db50dfdcc3bd2439517b1b8a8654' 
  AND token = '71zdCY+zNOi70aiMqj3WXZGO710zXr2b2/EJ1tOIP94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}