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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb6a2ab7891842d2a4d3b76af4751f5807a1486605412dfeb2d116b50aeb0af' 
  AND token = '+VRDOL7md1W2sJ/XAsfpIM0i4pSTpgQ0nAQZzRJRBqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}