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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3421a6e99c09065eed14691a990864c407367ec6f72f5c98085e019d8dde5baa' 
  AND token = 'D33d0y2eMWubdwN+XG1I5E+jDEEYtoo57FFmXFZRDJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}