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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02218075b751c704e5dded2d6624d49cc59ca33a324365e98d195a6a67755a6e' 
  AND token = 'tCNvH3lgaNQcKqSNlIEWngDs8HT8CzdDRpPA5fqUgWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}