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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd4adf8fb231b304cedf9f88cad35ea287bd611767d2925997bb6aec2141d5a' 
  AND token = 'EQXK7GtwDl5LjwaX86VdqI4LR2RO5WX/U4m90jjEtfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}