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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f78e6ce110094c2d8501f3b8debeec5d03f82cf6db15b89e6370d538728c6c1f' 
  AND token = 'xdeQG3z9TYRIjgL4QKGdA/6LQieBOxjUPgQg+qMPEbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}